It worked fine, the only real problem being that my phone is really uncomfortable to use that way -- I had to set it down every time we shuffled, and in Dominion you shuffle a lot.
The first game we played one of the standard spreads, and despite a couple really flashy turns on my part (like when I played festivals to get my hand down to one, then used a library and got a total of 16 copper to buy two provinces in the same turn) it ended up as a tie.
The second game was random... lots of attacks, including the witch. No defense. No cellar. No extra actions except for a couple cantrips. Nothing. There was a remodel to get rid of curses, but...
Yeah. It was a long game. The witch stack ran out first, followed by the 'spy' stack since it was the 4-cost cantrip and I just kept buying them because they were fun. The third stack to run out, eventually, was curses. Final score? I lost with -3 points to Rowyn's zero. x.x But it was still fun, even though we were both struggling. >:) Dominion's that sort of game -- usually when you're having a hard time because of an unfavorable setup, so is everyone else.